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Chemical structure of Bi-Mc-VC-PAB-MMAE

GC68764

Bi-Mc-VC-PAB-MMAE

Also known as [4-[[(2S)-2-[[(2S)-2-[[2-[1,3-bis(2,5-dioxopyrrol-1-yl)propan-2-yloxy]acetyl]amino]-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate

Bi-Mc-VC-PAB-MMAE is composed of an ADC linker (Fmoc-Val-Cit-PAB) and MMAE, which is an effective inhibitor of tubulin· Bi-Mc-VC-PAB-MMAE can be used for antibody conjugation

ChemicalCAS1620837-70-8MW1413.66FormulaC71H104N12O18
CAS number
1620837-70-8
Molecular weight
1413.66
Formula
C71H104N12O18
Solubility
DMSO ： 100 mg/mL (70·74 mM; Need ultrasonic)
InChIKey
LGNKBBQOTXBJFY-USLNFXPWSA-N
Catalogue number
GC68764
Brand
GLPBIO
Computed properties PubChem CID 118547250 · XLogP 3.1 · TPSA 393 Ų · H-bond donors 8
XLogP
3.1
TPSA
393 Ų
H-bond donors
8
H-bond acceptors
18
Rotatable bonds
40
Heavy atoms
101

SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)COC(CN4C(=O)C=CC4=O)CN5C(=O)C=CC5=O

Computed descriptors from PubChem (CID 118547250), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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