Loading...
Chemical structure of Bamocaftor

GC68723

Bamocaftor

Also known as N-(benzenesulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore the function of F508del-CFTR protein· Bamocaftor can be used in combination with Tezacaftor and Ivacaftor for research on cystic fibrosis

ChemicalCAS2204245-48-5MW591.64FormulaC28H32F3N5O4S
CAS number
2204245-48-5
Molecular weight
591.64
Formula
C28H32F3N5O4S
Solubility
DMSO ： 100 mg/mL (169·02 mM; ultrasonic and warming and heat to 60°C)
InChIKey
IGEOJNMYRZUKIK-IBGZPJMESA-N
Catalogue number
GC68723
Brand
GLPBIO
Computed properties PubChem CID 134393443 · XLogP 5.9 · TPSA 115 Ų · H-bond donors 1
XLogP
5.9
TPSA
115 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
9
Heavy atoms
41

SMILES C[C@H]1CC(N(C1)C2=C(C=CC(=N2)N3C=CC(=N3)OCCC4(CC4)C(F)(F)F)C(=O)NS(=O)(=O)C5=CC=CC=C5)(C)C

Computed descriptors from PubChem (CID 134393443), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.