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Chemical structure of Antiviral agent 24

GC68675

Antiviral agent 24

Also known as (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[3-(trifluoromethyl)phenyl]methylamino]purin-9-yl]oxolane-3,4-diol

Antiviral agent 24 is an effective antiviral agent with EC50 values of 0·101, 19·9, and 91·2 µM against EV71, CVA21, and EV68 respectively· Antiviral agent 24 inhibits the activity of METTL3/METTL14 in a dose-dependent manner

ChemicalCAS23661-03-2MW425.36FormulaC18H18F3N5O4
CAS number
23661-03-2
Molecular weight
425.36
Formula
C18H18F3N5O4
Solubility
DMSO : 250 mg/mL (587·74 mM; Need ultrasonic)
InChIKey
SDQKDCSBWUSBDO-LSCFUAHRSA-N
Catalogue number
GC68675
Brand
GLPBIO
Computed properties PubChem CID 44423866 · XLogP 2 · TPSA 126 Ų · H-bond donors 4
XLogP
2
TPSA
126 Ų
H-bond donors
4
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
30

SMILES C1=CC(=CC(=C1)C(F)(F)F)CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

Computed descriptors from PubChem (CID 44423866), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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