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Chemical structure of ALM301

GC68640

ALM301

Also known as 6-[4-(1-amino-3-hydroxycyclobutyl)phenyl]-1-ethyl-7-phenylpyrido[2,3-b][1,4]oxazin-2-one

ALM301 is a highly specific AKT inhibitor with oral activity· Its IC50 values for AKT1, AKT2 and AKT3 are 0·13 μM, 0·09 μM and 2·75 μM, respectively· ALM301 inhibits the phosphorylation of AKT and regulates downstream signaling in vitro· It can inhibit cancer cell proliferation and tumor growth

ChemicalCAS1313439-71-2MW415.48FormulaC25H25N3O3
CAS number
1313439-71-2
Molecular weight
415.48
Formula
C25H25N3O3
Solubility
DMSO ： 50 mg/mL (120·34 mM; Need ultrasonic)
InChIKey
BPHCAPAOSHZYJY-UHFFFAOYSA-N
Catalogue number
GC68640
Brand
GLPBIO
Computed properties PubChem CID 68299673 · XLogP 2.6 · TPSA 88.7 Ų · H-bond donors 2
XLogP
2.6
TPSA
88.7 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
31

SMILES CCN1C(=O)COC2=C1C=C(C(=N2)C3=CC=C(C=C3)C4(CC(C4)O)N)C5=CC=CC=C5

Computed descriptors from PubChem (CID 68299673), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.