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Chemical structure of ABBV-318

GC68591

ABBV-318

Also known as [(3R)-3-fluoropyrrolidin-1-yl]-[6-[[5-(trifluoromethyl)-2-pyridinyl]oxy]quinolin-2-yl]methanone

ABBV-318 is an effective Nav1·7/Nav1·8 blocker, with IC50 values of 2·8 μM and 3·8 μM for hNav1·7 and hNav1·8 inhibition, respectively· ABBV-318 can be used in pain-related research

ChemicalCAS1802848-94-7MW405.35FormulaC20H15F4N3O2
CAS number
1802848-94-7
Molecular weight
405.35
Formula
C20H15F4N3O2
Solubility
DMSO ： 166·67 mg/mL (411·18 mM; Need ultrasonic)
InChIKey
FWLFRXVPNVBXGR-CQSZACIVSA-N
Catalogue number
GC68591
Brand
GLPBIO
Computed properties PubChem CID 118273623 · XLogP 4.2 · TPSA 55.3 Ų · H-bond donors 0
XLogP
4.2
TPSA
55.3 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
29

SMILES C1CN(C[C@@H]1F)C(=O)C2=NC3=C(C=C2)C=C(C=C3)OC4=NC=C(C=C4)C(F)(F)F

Computed descriptors from PubChem (CID 118273623), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.