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Chemical structure of 8-Azanebularine

GC68581

8-Azanebularine

Also known as (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(triazolo[4,5-d]pyrimidin-3-yl)oxolane-3,4-diol

8-Azanebularine is a compound that replaces the C6 amino group with hydrogen and inhibits ADAR2 reaction at high concentrations (IC50=15 mM)· When incorporated into RNA structures recognized by human ADAR2, 8-Azanebularine binds with high affinity (KD=2 nM)· It can be used for studying RNA editing reactions catalyzed by ADAR

ChemicalCAS38874-46-3MW253.21FormulaC9H11N5O4
CAS number
38874-46-3
Molecular weight
253.21
Formula
C9H11N5O4
Solubility
DMSO ： 50 mg/mL (197·46 mM; Need ultrasonic); H2O ： 5 mg/mL (19·75 mM; Need ultrasonic)
InChIKey
XOUCEKYAMMLQRC-JXOAFFINSA-N
Catalogue number
GC68581
Brand
GLPBIO
Computed properties PubChem CID 10106291 · XLogP -1.9 · TPSA 126 Ų · H-bond donors 3
XLogP
-1.9
TPSA
126 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
18

SMILES C1=C2C(=NC=N1)N(N=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O

Computed descriptors from PubChem (CID 10106291), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.