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Chemical structure of 5-Azidomethyl-uridine

GC68563

5-Azidomethyl-uridine

Also known as 5-(azidomethyl)-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

5-Azidomethyl-uridine is a point chemical reagent containing an azide group· It may be used as a substitute for BrU (5-bromouridine) or 5-EU (5-ethynyluridine) in copper-catalyzed detection of new RNA synthesis in proliferating cells· 5-AmU is cell-permeable and may bind to newly synthesized RNA instead of its natural analogue uridine· This hypothesis is based on the previously demonstrated applicability of 5-AmdU (5-azido-methyl-deoxyuridine) for monitoring DNA synthesis and 5-AmUTP (5-azido-methyl-UTP) for monitoring RNA synthesis

ChemicalCAS24751-67-5MW299.24FormulaC10H13N5O6
CAS number
24751-67-5
Molecular weight
299.24
Formula
C10H13N5O6
Solubility
DMSO ： 125 mg/mL (417·72 mM; Need ultrasonic)
InChIKey
ZAFBFGDCEFQDFD-JXOAFFINSA-N
Catalogue number
GC68563
Brand
GLPBIO
Computed properties PubChem CID 121487445 · XLogP -1.1 · TPSA 134 Ų · H-bond donors 4
XLogP
-1.1
TPSA
134 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
21

SMILES C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)CN=[N+]=[N-]

Computed descriptors from PubChem (CID 121487445), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.