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Chemical structure of Bis-Tos-(2-hydroxyethyl disulfide)

GC67539

Bis-Tos-(2-hydroxyethyl disulfide)

Also known as 2-[2-(4-methylphenyl)sulfonyloxyethyldisulfanyl]ethyl 4-methylbenzenesulfonate

Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS69981-39-1MW462.62FormulaC18H22O6S4
CAS number
69981-39-1
Molecular weight
462.62
Formula
C18H22O6S4
InChIKey
BBGVCMPJFAYXLJ-UHFFFAOYSA-N
Catalogue number
GC67539
Brand
GLPBIO
Computed properties PubChem CID 12452547 · XLogP 3.6 · TPSA 154 Ų · H-bond donors 0
XLogP
3.6
TPSA
154 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
11
Heavy atoms
28

SMILES CC1=CC=C(C=C1)S(=O)(=O)OCCSSCCOS(=O)(=O)C2=CC=C(C=C2)C

Computed descriptors from PubChem (CID 12452547), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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