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Chemical structure of Thalidomide-NH-C10-COOH

GC67530

Thalidomide-NH-C10-COOH

Also known as 11-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]undecanoic acid

Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based von Hippel-Lindau (VHL) ligand and a linker used in PROTAC technology

ChemicalCAS2428400-33-1MW457.52FormulaC24H31N3O6
CAS number
2428400-33-1
Molecular weight
457.52
Formula
C24H31N3O6
InChIKey
ZVXZSTZZOBYFRQ-UHFFFAOYSA-N
Catalogue number
GC67530
Brand
GLPBIO
Computed properties PubChem CID 145925674 · XLogP 4.1 · TPSA 133 Ų · H-bond donors 3
XLogP
4.1
TPSA
133 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
13
Heavy atoms
33

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCCCCCCCC(=O)O

Computed descriptors from PubChem (CID 145925674), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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