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Chemical structure of Tiazofurin

GC67477

Tiazofurin

Also known as 2-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide

Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity· Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH)· Tiazofurin also has anti-orthopoxvirus and anti-variola activities

ChemicalCAS60084-10-8MW260.27FormulaC9H12N2O5S
CAS number
60084-10-8
Molecular weight
260.27
Formula
C9H12N2O5S
InChIKey
FVRDYQYEVDDKCR-UHFFFAOYSA-N
Catalogue number
GC67477
Brand
GLPBIO
Computed properties PubChem CID 323701 · XLogP -1.7 · TPSA 154 Ų · H-bond donors 4
XLogP
-1.7
TPSA
154 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
17

SMILES C1=C(N=C(S1)C2C(C(C(O2)CO)O)O)C(=O)N

Computed descriptors from PubChem (CID 323701), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.