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Chemical structure of NO2-SPP

GC67189

NO2-SPP

Also known as (2,5-dioxopyrrolidin-1-yl) 4-[(5-nitro-2-pyridinyl)disulfanyl]pentanoate

NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC)

ChemicalCAS663598-61-6MW385.42FormulaC14H15N3O6S2
CAS number
663598-61-6
Molecular weight
385.42
Formula
C14H15N3O6S2
InChIKey
JFSJKWBYKAONEH-UHFFFAOYSA-N
Catalogue number
GC67189
Brand
GLPBIO
Computed properties PubChem CID 22382871 · XLogP 1.3 · TPSA 173 Ų · H-bond donors 0
XLogP
1.3
TPSA
173 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
25

SMILES CC(CCC(=O)ON1C(=O)CCC1=O)SSC2=NC=C(C=C2)[N+](=O)[O-]

Computed descriptors from PubChem (CID 22382871), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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