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Chemical structure of Biotin-PEG8-NHS ester

GC66973

Biotin-PEG8-NHS ester

Also known as (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS2143968-03-8MW764.88FormulaC33H56N4O14S
CAS number
2143968-03-8
Molecular weight
764.88
Formula
C33H56N4O14S
InChIKey
YCGZDGOCJORRHA-IUEKTVKYSA-N
Catalogue number
GC66973
Brand
GLPBIO
Computed properties PubChem CID 77078238 · XLogP -2.2 · TPSA 233 Ų · H-bond donors 3
XLogP
-2.2
TPSA
233 Ų
H-bond donors
3
H-bond acceptors
15
Rotatable bonds
34
Heavy atoms
52

SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@H]2[C@@H]3[C@H](CS2)NC(=O)N3

Computed descriptors from PubChem (CID 77078238), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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