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Chemical structure of Dimethylamine-SPDB

GC66848

Dimethylamine-SPDB

Also known as (2,5-dioxopyrrolidin-1-yl) 2-(dimethylamino)-4-(pyridin-2-yldisulfanyl)butanoate

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS1193111-73-7MW369.46FormulaC15H19N3O4S2
CAS number
1193111-73-7
Molecular weight
369.46
Formula
C15H19N3O4S2
InChIKey
DVABDPJDROOSBH-UHFFFAOYSA-N
Catalogue number
GC66848
Brand
GLPBIO
Computed properties PubChem CID 57945508 · XLogP 1.2 · TPSA 130 Ų · H-bond donors 0
XLogP
1.2
TPSA
130 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
24

SMILES CN(C)C(CCSSC1=CC=CC=N1)C(=O)ON2C(=O)CCC2=O

Computed descriptors from PubChem (CID 57945508), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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