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Chemical structure of Mal-Sulfo-DBCO

GC66826

Mal-Sulfo-DBCO

Also known as 1-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]-1-oxopropane-2-sulfonic acid

Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS2028281-86-7MW578.59FormulaC28H26N4O8S
CAS number
2028281-86-7
Molecular weight
578.59
Formula
C28H26N4O8S
InChIKey
IQQMMWCHYXQNOT-UHFFFAOYSA-N
Catalogue number
GC66826
Brand
GLPBIO
Computed properties PubChem CID 123132095 · XLogP -0.4 · TPSA 179 Ų · H-bond donors 3
XLogP
-0.4
TPSA
179 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
41

SMILES C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)C(CNC(=O)CCN4C(=O)C=CC4=O)S(=O)(=O)O

Computed descriptors from PubChem (CID 123132095), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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