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Chemical structure of Mal-amido-PEG3-C1-NHS ester

GC66817

Mal-amido-PEG3-C1-NHS ester

Also known as (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]acetate

Mal-amido-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS2101206-45-3MW455.42FormulaC19H25N3O10
CAS number
2101206-45-3
Molecular weight
455.42
Formula
C19H25N3O10
InChIKey
HMTNEILNSWIWRP-UHFFFAOYSA-N
Catalogue number
GC66817
Brand
GLPBIO
Computed properties PubChem CID 129896958 · XLogP -2.7 · TPSA 158 Ų · H-bond donors 1
XLogP
-2.7
TPSA
158 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
16
Heavy atoms
32

SMILES C1CC(=O)N(C1=O)OC(=O)COCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O

Computed descriptors from PubChem (CID 129896958), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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