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Chemical structure of Fmoc-N-methyl-PEG3-CH2CH2COOH

GC66813

Fmoc-N-methyl-PEG3-CH2CH2COOH

Also known as 3-[2-[2-[2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]ethoxy]ethoxy]ethoxy]propanoic acid

Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS1807518-77-9MW457.52FormulaC25H31NO7
CAS number
1807518-77-9
Molecular weight
457.52
Formula
C25H31NO7
InChIKey
JKEBDIJQSKVIID-UHFFFAOYSA-N
Catalogue number
GC66813
Brand
GLPBIO
Computed properties PubChem CID 91809450 · XLogP 2.3 · TPSA 94.5 Ų · H-bond donors 1
XLogP
2.3
TPSA
94.5 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
15
Heavy atoms
33

SMILES CN(CCOCCOCCOCCC(=O)O)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Computed descriptors from PubChem (CID 91809450), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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