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Chemical structure of 2'-O,4'-C-Methyleneguanosine

GC66655

2'-O,4'-C-Methyleneguanosine

Also known as 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one

2′-O,4′-C-Methyleneguanosine (LNA-G) is a reverse guanine analogue, where LNA (locked nucleic acid) is a nucleic acid analogue· LNA modification can be used in a variety of applications such as effective binding affinity to complementary sequences and greater nuclease resistance than natural nucleotides, offering great potential for applications in disease diagnosis and research· LNA-G is also available via KOD DNA polymerase, which allows the integration of LNA-G nucleotides into the DNA strand

ChemicalCAS207131-16-6MW295.25FormulaC11H13N5O5
CAS number
207131-16-6
Molecular weight
295.25
Formula
C11H13N5O5
InChIKey
OZVMOEUWPMYRQU-JUQFDLSGSA-N
Catalogue number
GC66655
Brand
GLPBIO
Computed properties PubChem CID 136404736 · XLogP -2.6 · TPSA 144 Ų · H-bond donors 4
XLogP
-2.6
TPSA
144 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
2
Heavy atoms
21

SMILES C1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)O)CO

Computed descriptors from PubChem (CID 136404736), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.