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Chemical structure of Azilsartan mepixetil

GC66468

Azilsartan mepixetil

Also known as 1-[(3,5,6-trimethylpyrazin-2-yl)methoxycarbonyloxy]ethyl 2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

Azilsartan mepixetil is the antagonist of angiotensin II receptor· Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety· Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions· Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A)

ChemicalCAS1596357-16-2MW678.69FormulaC36H34N6O8
CAS number
1596357-16-2
Molecular weight
678.69
Formula
C36H34N6O8
Solubility
DMSO : 200 mg/mL (294·69 mM; Need ultrasonic)
InChIKey
JXSDNNVNQNYJSP-UHFFFAOYSA-N
Catalogue number
GC66468
Brand
GLPBIO
Computed properties PubChem CID 137091385 · XLogP 6.1 · TPSA 165 Ų · H-bond donors 1
XLogP
6.1
TPSA
165 Ų
H-bond donors
1
H-bond acceptors
12
Rotatable bonds
14
Heavy atoms
50

SMILES CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)OC(C)OC(=O)OCC6=NC(=C(N=C6C)C)C

Computed descriptors from PubChem (CID 137091385), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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