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Chemical structure of BV02

GC66461

BV02

Also known as 2-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,3-dioxoisoindole-5-carboxylic acid

BV02 is a potent 4-3-3 PPI (14-3-3 protein-protein interaction) inhibitor· BV02 shows cytotoxicity for hematopoietic cells expressing the IM (imatinib mesylate)-sensitive wild type Bcr-Abl and the IM-resistant T315I mutation· BV02 has the potential for the research of chronic myeloid leukemia

ChemicalCAS292870-53-2MW377.35FormulaC20H15N3O5
CAS number
292870-53-2
Molecular weight
377.35
Formula
C20H15N3O5
Solubility
DMSO ： 11·36 mg/mL (30·10 mM; ultrasonic and warming and heat to 80°C)
InChIKey
ZFYSDSINNOLWGO-UHFFFAOYSA-N
Catalogue number
GC66461
Brand
GLPBIO
Computed properties PubChem CID 1087337 · XLogP 2.3 · TPSA 98.2 Ų · H-bond donors 1
XLogP
2.3
TPSA
98.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
28

SMILES CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N3C(=O)C4=C(C3=O)C=C(C=C4)C(=O)O

Computed descriptors from PubChem (CID 1087337), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.