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Chemical structure of UCB-5307

GC66460

UCB-5307

Also known as [1-[(2,5-dimethylphenyl)methyl]benzimidazol-2-yl]-pyridin-4-ylmethanol

UCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα· UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex

ChemicalCAS1515887-44-1MW343.42FormulaC22H21N3O
CAS number
1515887-44-1
Molecular weight
343.42
Formula
C22H21N3O
Solubility
DMSO : 50 mg/mL (145·59 mM; Need ultrasonic)
InChIKey
MKABLXAUPLCAHG-UHFFFAOYSA-N
Catalogue number
GC66460
Brand
GLPBIO
Computed properties PubChem CID 90033751 · XLogP 3.5 · TPSA 50.9 Ų · H-bond donors 1
XLogP
3.5
TPSA
50.9 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
26

SMILES CC1=CC(=C(C=C1)C)CN2C3=CC=CC=C3N=C2C(C4=CC=NC=C4)O

Computed descriptors from PubChem (CID 90033751), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.