GC66430
Fludarabine triphosphate trisodium
Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine, is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2·3 μM and a Ki of 6·1 μM· Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation· Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis
ChemicalMW591.12FormulaC10H12FN5Na3O13P3
- CAS number
- —
- Molecular weight
- 591.12
- Formula
- C10H12FN5Na3O13P3
- Solubility
- H2O ： 250 mg/mL (422·93 mM; Need ultrasonic)
- Catalogue number
- GC66430
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il