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Chemical structure of Tetraethylene glycol monotosylate

GC66232

Tetraethylene glycol monotosylate

Also known as 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS77544-60-6MW348.41FormulaC15H24O7S
CAS number
77544-60-6
Molecular weight
348.41
Formula
C15H24O7S
InChIKey
FGDJUEZBMFELRW-UHFFFAOYSA-N
Catalogue number
GC66232
Brand
GLPBIO
Computed properties PubChem CID 13456094 · XLogP 0.3 · TPSA 99.7 Ų · H-bond donors 1
XLogP
0.3
TPSA
99.7 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
13
Heavy atoms
23

SMILES CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCO

Computed descriptors from PubChem (CID 13456094), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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