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Chemical structure of Mc-?Val-?Ala-?PAB

GC66194

Mc-?Val-?Ala-?PAB

Also known as 6-(2,5-dioxopyrrol-1-yl)-N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]hexanamide

Mc-Val-Ala-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS1870916-87-2MW486.56FormulaC25H34N4O6
CAS number
1870916-87-2
Molecular weight
486.56
Formula
C25H34N4O6
InChIKey
DAMSURYLURICHN-SBUREZEXSA-N
Catalogue number
GC66194
Brand
GLPBIO
Computed properties PubChem CID 100029273 · XLogP 0.9 · TPSA 145 Ų · H-bond donors 4
XLogP
0.9
TPSA
145 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
13
Heavy atoms
35

SMILES C[C@@H](C(=O)NC1=CC=C(C=C1)CO)NC(=O)[C@H](C(C)C)NC(=O)CCCCCN2C(=O)C=CC2=O

Computed descriptors from PubChem (CID 100029273), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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