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Chemical structure of Cabotegravir sodium

GC66051

Cabotegravir sodium

Also known as sodium (3R,6S)-12-[(2,4-difluorophenyl)methylcarbamoyl]-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.03,7]trideca-9,12-dien-10-olate

Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2·5 nM, 0·41 μM and 0·81 μM for HIVADA, OAT3 and OAT1, respectively· Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral drugs (ARVs)· Cabotegravir sodium can be used to research AIDS

ChemicalCAS1051375-13-3MW427.33FormulaC19H16F2N3NaO5
CAS number
1051375-13-3
Molecular weight
427.33
Formula
C19H16F2N3NaO5
Solubility
DMSO ： 6·9 mg/mL (16·15 mM; ultrasonic and warming and heat to 60°C)
InChIKey
AEZBWGMXBKPGFP-KIUAEZIZSA-M
Catalogue number
GC66051
Brand
GLPBIO
Computed properties PubChem CID 46215800 · TPSA 102 Ų · H-bond donors 1 · H-bond acceptors 8
TPSA
102 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
30

SMILES C[C@H]1CO[C@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

Computed descriptors from PubChem (CID 46215800), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.