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Chemical structure of CDK5-IN-3

GC66009

CDK5-IN-3

Also known as (1R)-1-(7-anilino-1,6-naphthyridin-2-yl)-1-(1-methylpiperidin-4-yl)ethanol

CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0·6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively· CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)

ChemicalCAS2639542-32-6MW362.47FormulaC22H26N4O
CAS number
2639542-32-6
Molecular weight
362.47
Formula
C22H26N4O
Solubility
DMSO ： 10 mg/mL (27·59 mM; Need ultrasonic)
InChIKey
MLZPRAPIZUZUNO-JOCHJYFZSA-N
Catalogue number
GC66009
Brand
GLPBIO
Computed properties PubChem CID 156212722 · XLogP 3.2 · TPSA 61.3 Ų · H-bond donors 2
XLogP
3.2
TPSA
61.3 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
27

SMILES C[C@@](C1CCN(CC1)C)(C2=NC3=CC(=NC=C3C=C2)NC4=CC=CC=C4)O

Computed descriptors from PubChem (CID 156212722), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.