GC65986
SAE-14
Also known as 3-(3,4-difluorophenyl)-N-(3-fluoro-5-morpholin-4-ylphenyl)propanamide
SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28·5 nM, can antagonize 7α, 25-OHC-induced calcium mobilization with IC50 value below 50 nM in HL-60 cells· GPR183 antagonist-1 can reverse allodynia in mice
ChemicalCAS1241280-25-0MW364.36FormulaC19H19F3N2O2
- CAS number
- 1241280-25-0
- Molecular weight
- 364.36
- Formula
- C19H19F3N2O2
- Solubility
- DMSO ： 100 mg/mL (274·45 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- SIVJKYRAPQKLIM-UHFFFAOYSA-N
- Catalogue number
- GC65986
- Brand
- GLPBIO
Computed properties PubChem CID 47088557 · XLogP 3 · TPSA 41.6 Ų · H-bond donors 1
- XLogP
- 3
- TPSA
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 26
SMILES C1COCCN1C2=CC(=CC(=C2)NC(=O)CCC3=CC(=C(C=C3)F)F)F
Computed descriptors from PubChem (CID 47088557), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il