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Chemical structure of MMP13-IN-2

GC65957

MMP13-IN-2

Also known as 5-(3-fluorophenyl)-4-oxo-N-[[3-[2-(1H-1,2,4-triazol-5-yloxy)ethoxy]phenyl]methyl]-3H-thieno[2,3-d]pyrimidine-2-carboxamide

MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor· MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0·036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE· MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro· MMP13-IN-2 has the potential for collagenase related disease research

ChemicalCAS935759-55-0MW506.51FormulaC24H19FN6O4S
CAS number
935759-55-0
Molecular weight
506.51
Formula
C24H19FN6O4S
Solubility
DMSO ： 100 mg/mL (197·43 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MLUCCAMJMIYYED-UHFFFAOYSA-N
Catalogue number
GC65957
Brand
GLPBIO
Computed properties PubChem CID 16719301 · XLogP 3.7 · TPSA 159 Ų · H-bond donors 3
XLogP
3.7
TPSA
159 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
36

SMILES C1=CC(=CC(=C1)OCCOC2=NC=NN2)CNC(=O)C3=NC4=C(C(=CS4)C5=CC(=CC=C5)F)C(=O)N3

Computed descriptors from PubChem (CID 16719301), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.