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Chemical structure of KSQ-4279

GC65907

KSQ-4279

Also known as 6-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-1-[[4-[1-propan-2-yl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methyl]pyrazolo[3,4-d]pyrimidine

KSQ-4279 (USP1-IN-1, Formula I) is a USP1 and PARP inhibitor (extracted from patent WO2021163530)

ChemicalCAS2446480-97-1MW534.54FormulaC27H25F3N8O
CAS number
2446480-97-1
Molecular weight
534.54
Formula
C27H25F3N8O
Solubility
DMSO ： 80 mg/mL (149·66 mM; Need ultrasonic)
InChIKey
KCBWAFJCKVKYHO-UHFFFAOYSA-N
Catalogue number
GC65907
Brand
GLPBIO
Computed properties PubChem CID 150782011 · XLogP 4 · TPSA 96.4 Ų · H-bond donors 0
XLogP
4
TPSA
96.4 Ų
H-bond donors
0
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
39

SMILES CC(C)N1C=C(N=C1C2=CC=C(C=C2)CN3C4=NC(=NC=C4C=N3)C5=C(N=CN=C5OC)C6CC6)C(F)(F)F

Computed descriptors from PubChem (CID 150782011), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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