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Chemical structure of PCLX-001

GC65891

PCLX-001

Also known as 2,6-dichloro-N-[1,5-dimethyl-3-(2-methylpropyl)pyrazol-4-yl]-4-(2-piperazin-1-yl-4-pyridinyl)benzenesulfonamide

PCLX-001 is an orally acitve, small-molecule, dual N-myristoyltransferase (NMT) inhibitor, with IC50s of 5 nM (NMT1) and 8 nM (NMT2), respectively· PCLX-001 exhibits anti-tumor activity and inhibits early B-cell receptor (BCR) signaling, can be used to B-cell malignancies research

ChemicalCAS1215011-08-7MW537.51FormulaC24H30Cl2N6O2S
CAS number
1215011-08-7
Molecular weight
537.51
Formula
C24H30Cl2N6O2S
InChIKey
WKTSLVQYGBHNRV-UHFFFAOYSA-N
Catalogue number
GC65891
Brand
GLPBIO
Computed properties PubChem CID 58561243 · XLogP 4.4 · TPSA 101 Ų · H-bond donors 2
XLogP
4.4
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
35

SMILES CC1=C(C(=NN1C)CC(C)C)NS(=O)(=O)C2=C(C=C(C=C2Cl)C3=CC(=NC=C3)N4CCNCC4)Cl

Computed descriptors from PubChem (CID 58561243), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.