GC65877
(S)-GFB-12811
Also known as (1S)-1-[7-[[5-fluoro-2-(trifluoromethyl)-4-pyridinyl]amino]-1,6-naphthyridin-2-yl]-1-(1-methylpiperidin-4-yl)ethanol
(S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM· (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis
ChemicalCAS2757672-69-6MW449.44FormulaC22H23F4N5O
- CAS number
- 2757672-69-6
- Molecular weight
- 449.44
- Formula
- C22H23F4N5O
- InChIKey
- GHNYLVIESIGHDJ-NRFANRHFSA-N
- Catalogue number
- GC65877
- Brand
- GLPBIO
Computed properties PubChem CID 163360073 · XLogP 3.1 · TPSA 74.2 Ų · H-bond donors 2
- XLogP
- 3.1
- TPSA
- 74.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Rotatable bonds
- 4
- Heavy atoms
- 32
SMILES C[C@](C1CCN(CC1)C)(C2=NC3=CC(=NC=C3C=C2)NC4=CC(=NC=C4F)C(F)(F)F)O
Computed descriptors from PubChem (CID 163360073), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il