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Chemical structure of Propargyl-PEG1-acid

GC65856

Propargyl-PEG1-acid

Also known as 3-prop-2-ynoxypropanoic acid

Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib(HY-10997)-based PROTAC 4 and PROTAC 5· PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 μM

ChemicalCAS55683-37-9MW128.13FormulaC6H8O3
CAS number
55683-37-9
Molecular weight
128.13
Formula
C6H8O3
InChIKey
GMFDYXLFHSFUHE-UHFFFAOYSA-N
Catalogue number
GC65856
Brand
GLPBIO
Computed properties PubChem CID 287934 · XLogP -0.3 · TPSA 46.5 Ų · H-bond donors 1
XLogP
-0.3
TPSA
46.5 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
9

SMILES C#CCOCCC(=O)O

Computed descriptors from PubChem (CID 287934), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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