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Chemical structure of Fmoc-NH-PEG5-CH2COOH

GC65835

Fmoc-NH-PEG5-CH2COOH

Also known as 2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)· Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

ChemicalCAS635287-26-2MW517.57FormulaC27H35NO9
CAS number
635287-26-2
Molecular weight
517.57
Formula
C27H35NO9
InChIKey
LNIFRTLAPAPKAG-UHFFFAOYSA-N
Catalogue number
GC65835
Brand
GLPBIO
Computed properties PubChem CID 58687705 · XLogP 1.9 · TPSA 122 Ų · H-bond donors 2
XLogP
1.9
TPSA
122 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
20
Heavy atoms
37

SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCC(=O)O

Computed descriptors from PubChem (CID 58687705), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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