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Chemical structure of M4 mAChR agonist-1

GC65567

M4 mAChR agonist-1

Also known as 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4

ChemicalCAS785705-53-5MW290.38FormulaC14H18N4OS
CAS number
785705-53-5
Molecular weight
290.38
Formula
C14H18N4OS
Solubility
DMSO : 20 mg/mL (68·88 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 70°C)
InChIKey
KOMCJGHOPXNACW-UHFFFAOYSA-N
Catalogue number
GC65567
Brand
GLPBIO
Computed properties PubChem CID 2091326 · XLogP 2.1 · TPSA 100 Ų · H-bond donors 1
XLogP
2.1
TPSA
100 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
20

SMILES CC1=C(SC2=NC=NC(=C12)N3CCC(CC3)C(=O)N)C

Computed descriptors from PubChem (CID 2091326), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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