GC65510
ERK1/2 inhibitor 1
Also known as (2R)-2-[5-[5-chloro-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxo-1H-isoindol-2-yl]-N-[(1S)-2-hydroxy-1-(3-methylphenyl)ethyl]propanamide
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3·0 nM against ERK1 and ERK2, respectively
ChemicalCAS2095719-90-5MW550.05FormulaC29H32ClN5O4
- CAS number
- 2095719-90-5
- Molecular weight
- 550.05
- Formula
- C29H32ClN5O4
- Solubility
- DMSO ： 250 mg/mL (454·50 mM; Need ultrasonic)
- InChIKey
- XHOJEECXVUMYMF-IQGLISFBSA-N
- Catalogue number
- GC65510
- Brand
- GLPBIO
Computed properties PubChem CID 129053491 · XLogP 3.2 · TPSA 117 Ų · H-bond donors 3
- XLogP
- 3.2
- TPSA
- 117 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 39
SMILES CC1=CC(=CC=C1)[C@@H](CO)NC(=O)[C@@H](C)N2CC3=C(C2=O)C=C(C=C3)C4=NC(=NC=C4Cl)NC5CCOCC5
Computed descriptors from PubChem (CID 129053491), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il