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Chemical structure of Gly-Gly-Gly-PEG4-DBCO

GC65464

Gly-Gly-Gly-PEG4-DBCO

Also known as N-[2-[2-[2-[2-[2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-4-oxobutanamide

Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS2353409-80-8MW694.77FormulaC35H46N6O9
CAS number
2353409-80-8
Molecular weight
694.77
Formula
C35H46N6O9
InChIKey
IQIPCHLKYRUJEB-UHFFFAOYSA-N
Catalogue number
GC65464
Brand
GLPBIO
Computed properties PubChem CID 137334056 · XLogP -1.4 · TPSA 200 Ų · H-bond donors 5
XLogP
-1.4
TPSA
200 Ų
H-bond donors
5
H-bond acceptors
10
Rotatable bonds
23
Heavy atoms
50

SMILES C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCC(=O)NCCOCCOCCOCCOCCNC(=O)CNC(=O)CNC(=O)CN

Computed descriptors from PubChem (CID 137334056), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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