GC65311
Voruciclib hydrochloride
Also known as 2-[2-chloro-4-(trifluoromethyl)phenyl]-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochloride
Voruciclib hydrochloride is an orally active and selective CDK inhibitor with Ki values of 0·626 nM-9·1 nM· Voruciclib hydrochloride potently blocks CDK9, the transcriptional regulator of MCL-1· Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL)
ChemicalCAS1000023-05-1MW506.3FormulaC22H20Cl2F3NO5
- CAS number
- 1000023-05-1
- Molecular weight
- 506.3
- Formula
- C22H20Cl2F3NO5
- Solubility
- DMSO ： ≥ 250 mg/mL (493·78 mM)
- InChIKey
- QCWRANLELLMJSH-OJMBIDBESA-N
- Catalogue number
- GC65311
- Brand
- GLPBIO
Computed properties PubChem CID 67409218 · TPSA 90.2 Ų · H-bond donors 4 · H-bond acceptors 9
- TPSA
- 90.2 Ų
- H-bond donors
- 4
- H-bond acceptors
- 9
- Rotatable bonds
- 3
- Heavy atoms
- 33
SMILES CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=C(C=C(C=C4)C(F)(F)F)Cl)O)O.Cl
Computed descriptors from PubChem (CID 67409218), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il