Loading...
Chemical structure of S130

GC65307

S130

Also known as N-[3-(diethylamino)propyl]-8-oxo-10-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9,11,13(17),14-octaene-12-carboxamide

S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC50 of 3·24 ?M· S130 suppresses autophagy flux

ChemicalCAS1160852-22-1MW387.47FormulaC24H25N3O2
CAS number
1160852-22-1
Molecular weight
387.47
Formula
C24H25N3O2
Solubility
DMSO ： 125 mg/mL (322·61 mM; Need ultrasonic)
InChIKey
DZUCZYXRADUTMW-UHFFFAOYSA-N
Catalogue number
GC65307
Brand
GLPBIO
Computed properties PubChem CID 44128205 · XLogP 4 · TPSA 62.3 Ų · H-bond donors 1
XLogP
4
TPSA
62.3 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
29

SMILES CCN(CC)CCCNC(=O)C1=CN=C2C3=C1C=CC=C3C4=CC=CC=C4C2=O

Computed descriptors from PubChem (CID 44128205), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.