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Chemical structure of SDZ-MKS 492

GC65302

SDZ-MKS 492

Also known as 8-[[(1R)-1-(3,4-dimethoxyphenyl)-2-hydroxyethyl]amino]-7-(2-methoxyethyl)-1,3-dimethylpurine-2,6-dione

SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE)

ChemicalCAS114606-56-3MW433.46FormulaC20H27N5O6
CAS number
114606-56-3
Molecular weight
433.46
Formula
C20H27N5O6
Solubility
DMSO : 250 mg/mL (576·75 mM; Need ultrasonic)
InChIKey
VZLFAVFWNOZVFM-ZDUSSCGKSA-N
Catalogue number
GC65302
Brand
GLPBIO
Computed properties PubChem CID 163931 · XLogP 0.5 · TPSA 118 Ų · H-bond donors 2
XLogP
0.5
TPSA
118 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
31

SMILES CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)N[C@@H](CO)C3=CC(=C(C=C3)OC)OC)CCOC

Computed descriptors from PubChem (CID 163931), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.