GC65298
DMX-5804
Also known as 5-[4-(2-methoxyethoxy)phenyl]-7-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4-one
DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8·55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8·18), and TNIK/MAP4K7 (pIC50, 7·96)
ChemicalCAS2306178-56-1MW361.39FormulaC21H19N3O3
- CAS number
- 2306178-56-1
- Molecular weight
- 361.39
- Formula
- C21H19N3O3
- Solubility
- DMSO ： 125 mg/mL (345·89 mM; Need ultrasonic)
- InChIKey
- FUSHFOGORKZNNQ-UHFFFAOYSA-N
- Catalogue number
- GC65298
- Brand
- GLPBIO
Computed properties PubChem CID 137334091 · XLogP 2.9 · TPSA 64.9 Ų · H-bond donors 1
- XLogP
- 2.9
- TPSA
- 64.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 6
- Heavy atoms
- 27
SMILES COCCOC1=CC=C(C=C1)C2=CN(C3=C2C(=O)NC=N3)C4=CC=CC=C4
Computed descriptors from PubChem (CID 137334091), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il