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Chemical structure of SLMP53-1

GC65284

SLMP53-1

Also known as (3S,9bR)-3-(1H-indol-3-ylmethyl)-9b-methyl-2,3-dihydro-[1,3]oxazolo[2,3-a]isoindol-5-one

SLMP53-1 is a wild-type and mutant p53 reactivator with promising antitumor activity· SLMP53-1 mediates the reprograming of glucose metabolism in cancer cells· SLMP53-1 depletes angiogenesis, decreasing endothelial cell tube formation and vascular endothelial growth factor (VEGF) expression levels

ChemicalCAS1643469-17-3MW318.37FormulaC20H18N2O2
CAS number
1643469-17-3
Molecular weight
318.37
Formula
C20H18N2O2
Solubility
DMSO : 250 mg/mL (785·25 mM; ultrasonic and warming and heat to 80°C)
InChIKey
RSAFMLBHKXOCJG-VBKZILBWSA-N
Catalogue number
GC65284
Brand
GLPBIO
Computed properties PubChem CID 86346168 · XLogP 3.1 · TPSA 45.3 Ų · H-bond donors 1
XLogP
3.1
TPSA
45.3 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
24

SMILES C[C@@]12C3=CC=CC=C3C(=O)N1[C@H](CO2)CC4=CNC5=CC=CC=C54

Computed descriptors from PubChem (CID 86346168), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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