Loading...
Chemical structure of Runcaciguat

GC65192

Runcaciguat

Also known as (3S)-3-[4-chloro-3-[[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino]phenyl]-3-cyclopropylpropanoic acid

Runcaciguat is an orally active stimulator of soluble guanylate cyclase, and is used in the research of cardiovascular and renal diseases combined with selective partial adenosine A1 receptor agonists

ChemicalCAS1402936-61-1MW488.33FormulaC23H22Cl2F3NO3
CAS number
1402936-61-1
Molecular weight
488.33
Formula
C23H22Cl2F3NO3
Solubility
DMSO ： 125 mg/mL (255·97 mM; Need ultrasonic)
InChIKey
NCRMKIWHFXSBGZ-CNBXIYLPSA-N
Catalogue number
GC65192
Brand
GLPBIO
Computed properties PubChem CID 134440946 · XLogP 6.6 · TPSA 66.4 Ų · H-bond donors 2
XLogP
6.6
TPSA
66.4 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
32

SMILES C[C@H]([C@@H](C1=CC=C(C=C1)Cl)C(=O)NC2=C(C=CC(=C2)[C@@H](CC(=O)O)C3CC3)Cl)C(F)(F)F

Computed descriptors from PubChem (CID 134440946), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.