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Chemical structure of P-gp inhibitor 1

GC65183

P-gp inhibitor 1

Also known as N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-2-pyridin-4-ylquinazolin-4-amine

P-gp inhibitor 1 is a novel inhibitor reversing P-glycoprotein-mediated multidrug resistance

ChemicalCAS2050747-49-2MW517.62FormulaC32H31N5O2
CAS number
2050747-49-2
Molecular weight
517.62
Formula
C32H31N5O2
Solubility
DMSO : 16·67 mg/mL (32·21 mM; ultrasonic and warming and heat to 70°C)
InChIKey
TXKOCTPGTLRGNL-UHFFFAOYSA-N
Catalogue number
GC65183
Brand
GLPBIO
Computed properties PubChem CID 132822387 · XLogP 5.8 · TPSA 72.4 Ų · H-bond donors 1
XLogP
5.8
TPSA
72.4 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
39

SMILES COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC4=NC(=NC5=CC=CC=C54)C6=CC=NC=C6)OC

Computed descriptors from PubChem (CID 132822387), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
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