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Chemical structure of CTX-712

GC65023

CTX-712

Also known as 2-[(1R)-1-fluoroethyl]-5-[[6-(4-methoxypyrrolo[2,1-f][1,2,4]triazin-5-yl)-2-methylimidazo[4,5-b]pyridin-1-yl]methyl]-1,3,4-oxadiazole

CTX-712 is a potent inhibitor of cdc2-like kinase (CLK)· CTX-712 inhibits CLK kinase activity, and thus inhibits cancer survival and cancer cell growth· CTX-712 has the potential for the research of cancer disease (extracted from patent JPWO2017188374A1, compound 286)

ChemicalCAS2144751-78-8MW408.39FormulaC19H17FN8O2
CAS number
2144751-78-8
Molecular weight
408.39
Formula
C19H17FN8O2
InChIKey
OENNTZBJPRRGFL-SNVBAGLBSA-N
Catalogue number
GC65023
Brand
GLPBIO
Computed properties PubChem CID 138522180 · XLogP 1.6 · TPSA 109 Ų · H-bond donors 0
XLogP
1.6
TPSA
109 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
30

SMILES CC1=NC2=C(N1CC3=NN=C(O3)[C@@H](C)F)C=C(C=N2)C4=C5C(=NC=NN5C=C4)OC

Computed descriptors from PubChem (CID 138522180), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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