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Chemical structure of CD38 inhibitor 1

GC64948

CD38 inhibitor 1

Also known as 4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one

CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7·3 nM and 1·9 nM for hCD38 and mouse CD38

ChemicalCAS1700637-55-3MW413.53FormulaC22H27N3O3S
CAS number
1700637-55-3
Molecular weight
413.53
Formula
C22H27N3O3S
Solubility
DMSO : 25 mg/mL (60·46 mM; ultrasonic and warming and heat to 60°C)
InChIKey
VJQALSOBHVEJQM-UHFFFAOYSA-N
Catalogue number
GC64948
Brand
GLPBIO
Computed properties PubChem CID 118736856 · XLogP 3 · TPSA 91.9 Ų · H-bond donors 1
XLogP
3
TPSA
91.9 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
29

SMILES CN1C2=C(C=C(C=C2)C3=CN=CS3)C(=CC1=O)NC4CCC(CC4)OCCOC

Computed descriptors from PubChem (CID 118736856), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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