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Chemical structure of AZD-7648

GC64938

AZD-7648

Also known as 7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one

AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0·6 nM· AZD-7648 induces apoptosis and shows antitumor activity

ChemicalCAS2230820-11-6MW380.4FormulaC18H20N8O2
CAS number
2230820-11-6
Molecular weight
380.4
Formula
C18H20N8O2
Solubility
DMSO ： 5 mg/mL (13·14 mM; ultrasonic and warming and heat to 80°C)
InChIKey
XISVSTPEXYIKJL-UHFFFAOYSA-N
Catalogue number
GC64938
Brand
GLPBIO
Computed properties PubChem CID 135151360 · XLogP 1 · TPSA 101 Ų · H-bond donors 1
XLogP
1
TPSA
101 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
28

SMILES CC1=CC2=NC=NN2C=C1NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCOCC5

Computed descriptors from PubChem (CID 135151360), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.