GC64920
SR-1114
Also known as N-cyclobutyl-2-[3-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethoxy]ethylsulfamoylamino]phenyl]imidazo[1,2-a]pyridine-6-carboxamide
SR-1114 is a first-in-class PROTAC ENL degrader· SR-1114 elicits rapid, CRBN-dependent degradation of ENL with DC50s of 150 nM, 311 nM, and 1·65 μM in MV4;11 , MOLM-13, and OCI/AML-2 cells, respectively
ChemicalCAS2769141-82-2MW830.86FormulaC39H42N8O11S
- CAS number
- 2769141-82-2
- Molecular weight
- 830.86
- Formula
- C39H42N8O11S
- InChIKey
- WPVVPCVQEBQVLL-UHFFFAOYSA-N
- Catalogue number
- GC64920
- Brand
- GLPBIO
Computed properties PubChem CID 155925846 · XLogP 1.2 · TPSA 253 Ų · H-bond donors 5
- XLogP
- 1.2
- TPSA
- 253 Ų
- H-bond donors
- 5
- H-bond acceptors
- 14
- Rotatable bonds
- 19
- Heavy atoms
- 59
SMILES C1CC(C1)NC(=O)C2=CN3C=C(N=C3C=C2)C4=CC(=CC=C4)NS(=O)(=O)NCCOCCOCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O
Computed descriptors from PubChem (CID 155925846), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il