GC64878
Factor D inhibitor 6
Also known as 1-[2-[(1R,3S,5R)-3-[[(1R)-1-(3-chloro-2-fluorophenyl)ethyl]carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxoethyl]pyrazolo[5,4-c]pyridine-3-carboxamide
Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC50 of 30 nM and a Kd of 6 nM
ChemicalCAS1386455-51-1MW484.91FormulaC23H22ClFN6O3
- CAS number
- 1386455-51-1
- Molecular weight
- 484.91
- Formula
- C23H22ClFN6O3
- Solubility
- DMSO ： 250 mg/mL (515·56 mM; Need ultrasonic)
- InChIKey
- YAALCKJNOOFODD-SKNMWMDOSA-N
- Catalogue number
- GC64878
- Brand
- GLPBIO
Computed properties PubChem CID 68283608 · XLogP 1.9 · TPSA 123 Ų · H-bond donors 2
- XLogP
- 1.9
- TPSA
- 123 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Rotatable bonds
- 6
- Heavy atoms
- 34
SMILES C[C@H](C1=C(C(=CC=C1)Cl)F)NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)CN4C5=C(C=CN=C5)C(=N4)C(=O)N
Computed descriptors from PubChem (CID 68283608), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il