Loading...
Chemical structure of GLUT inhibitor-1

GC64876

GLUT inhibitor-1

Also known as 2-[3-[6-cyclobutyl-4-[4-(1H-pyrazol-4-yl)anilino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-2-yl]phenoxy]-N-(1-methylcyclopropyl)acetamide

GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively

ChemicalCAS2421141-40-2MW549.67FormulaC32H35N7O2
CAS number
2421141-40-2
Molecular weight
549.67
Formula
C32H35N7O2
Solubility
DMSO ： 100 mg/mL (181·93 mM; ultrasonic and warming and heat to 60°C)
InChIKey
IXZVJTRRPOHKJF-UHFFFAOYSA-N
Catalogue number
GC64876
Brand
GLPBIO
Computed properties PubChem CID 156020834 · XLogP 4.5 · TPSA 108 Ų · H-bond donors 3
XLogP
4.5
TPSA
108 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
9
Heavy atoms
41

SMILES CC1(CC1)NC(=O)COC2=CC=CC(=C2)C3=NC4=C(CN(CC4)C5CCC5)C(=N3)NC6=CC=C(C=C6)C7=CNN=C7

Computed descriptors from PubChem (CID 156020834), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.