Loading...
Chemical structure of Gunagratinib

GC64875

Gunagratinib

Also known as 3-[2-(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrazole-4-carboxamide

Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding· Gunagratinib can be used for the research of cancer

ChemicalCAS2211082-53-8MW423.47FormulaC22H25N5O4
CAS number
2211082-53-8
Molecular weight
423.47
Formula
C22H25N5O4
InChIKey
QFUIJOBJAQBGDH-HNNXBMFYSA-N
Catalogue number
GC64875
Brand
GLPBIO
Computed properties PubChem CID 138734912 · XLogP 2.2 · TPSA 112 Ų · H-bond donors 2
XLogP
2.2
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
31

SMILES CNC1=C(C(=NN1[C@H]2CCN(C2)C(=O)C=C)C#CC3=CC(=CC(=C3)OC)OC)C(=O)N

Computed descriptors from PubChem (CID 138734912), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.