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Chemical structure of AMA-37

GC64818

AMA-37

Also known as (2-hydroxy-4-morpholin-4-ylphenyl)-phenylmethanone

AMA-37, an Arylmorpholine analog, is ATP-competitive DNA-PK inhibitor, with IC50 values of 0·27 μM (DNA-PK), 32 μM (p110α), 3·7 μM (p110β), and 22 μM (p110γ), respectively

ChemicalCAS404009-46-7MW283.32FormulaC17H17NO3
CAS number
404009-46-7
Molecular weight
283.32
Formula
C17H17NO3
InChIKey
FALILNHGILFDLC-UHFFFAOYSA-N
Catalogue number
GC64818
Brand
GLPBIO
Computed properties PubChem CID 16760391 · XLogP 3.2 · TPSA 49.8 Ų · H-bond donors 1
XLogP
3.2
TPSA
49.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
21

SMILES C1COCCN1C2=CC(=C(C=C2)C(=O)C3=CC=CC=C3)O

Computed descriptors from PubChem (CID 16760391), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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